The database includes: (i) Laboratory research and modelling on gene drives as reported in the academic literature and other sources such as press releases from funders and universities; (ii) Proposals for gene drives as identified from the natural sciences literature; (iii) Proposals deriving from other academic literature (such as literature relating to policy or ethics) are included at the discretion of the researchers, for example if such proposals designate novel targets; and (iv) The database covers gene drives and the closely related field of ‘sex ratio distorters’. ‘Horizontal Environmental Genetic Alteration Agents’ (HEGAAs) based on modified viruses may be included in the future pending further research and development. The database functions as a live literature review. Reports and publications are also periodically published through the database.